Stem Cells on the Joe Rogan Experience

“The BNP came down in every single case. The ejection fraction, which measures kind of like the efficiency, how much blood your heart's pumping on each stroke, …”

Riordan claims that in clinical trials, a heart-failure biomarker (BNP) decreased and ejection fraction increased in every single patient treated with stem cells.

“So President Obama in 2009 lifted the ban on the federal funding. So federal funding has been going on for it since then.”

The guest states that President Obama in 2009 lifted the ban on federal funding for (embryonic) stem cell research, after which federal funding continued.

“they injected that into the knee. And then I think, I want to say it was four or eight months later, I think it was eight months, they re-imaged the knee and t…”

The guest describes a study where injecting bone marrow aspirate (BMAC) stem cells into the knee produced a 15% increase in meniscal tissue volume on re-imaging.

“We just finished a clinical trial, prospective clinical trial. We submitted it for publication... And statistically, significantly, these patients improved dra…”

Riordan claims his company's own unpublished, self-run MS clinical trial (n=20) showed statistically significant dramatic improvement.

“It's technically not legal for someone to inject you with your own stem cells into your bloodstream, but if you get your stem cells extracted and they're store…”

Greenfield claims that while a clinic legally cannot inject a person's own stored stem cells into their bloodstream, it is legal for the person to inject the cells into themselves after the clinic mails the cells to their home.

“like for spinal cord injury, we did a cohort analysis, and basically if they're within one year of injury, 100% of the patients had restoration of some neurolo…”

Riordan claims his own cohort analysis found 100% of spinal cord injury patients treated within one year of injury regained some neurologic function, versus 82% between one and two years.

“We have 800 references, and we reference every clinical trial that's ever been done with MSCs in human beings, and there are 800 of them.”

Riordan claims his book references all 800 clinical trials ever conducted on mesenchymal stem cells in humans.

“they are the equivalent of what a typical dose we give in Panama is like roughly 120 million cells. And all of them got better. All of them symptomatically imp…”

Riordan claims a study of 172 rheumatoid arthritis patients given umbilical cord MSC infusions showed all patients improved symptomatically and TNF-alpha dropped 50%.

“there was a study at University of Buffalo where they took, they injected cells IV in a hamster model of heart failure. And then they looked in the heart and t…”

Riordan cites a University of Buffalo hamster study to claim MSC secretions alone (not the cells reaching the heart) reverse heart failure.

“a study out of Europe just came out a couple months ago, and it showed about 50% of the patients had their discs become normal on MRI after treatment. So it's …”

Riordan claims a recent European study found about 50% of patients had degenerated spinal discs return to normal on MRI after stem cell treatment.

“at last count, I think they spent, you know, two and three quarter billion dollars. They got $250 million left. And guess what they're studying now? Adult stem…”

Riordan claims California's embryonic stem cell program (CIRM, funded by the ~$3 billion Prop 71) spent nearly all its money and pivoted almost entirely to adult/umbilical cord stem cell research after embryonic approaches failed.

“Yeah, there's some really good animal data showing that you can inject these cells and you can take ovarian failure and reverse it. And in her case, she had an…”

Riordan claims stem cell treatment reversed ovarian failure and enabled a previously infertile patient to conceive, citing animal data as support for a human anecdote.

“And he was 11% ejection fraction. Normal is about 60. And the regular hospital who worked a lot with us with our spinal cord patients and seeing results, seein…”

Riordan recounts an anecdotal case of a patient with 11% ejection fraction being cured by stem cell treatment, implying dramatic heart failure reversal from a single anecdote.