Joe Rogan on health: what the evidence says · JRE #2082
SUBJECT: HEALTH
Not a true/false call. Every claim is logged with its sources; read the exhibits below.
now do you not are you not aware of the opioid crisis you're not aware of vioxx not aware of the various like to 25 percent of all fda approved drugs that get pulled it's one out of four
What the evidence says 01 / RECORD
Rogan claimed that roughly 25 percent, or "one out of four," of all FDA-approved drugs eventually get pulled from the market. Peer-reviewed postmarket surveillance research puts the actual withdrawal rate far lower: a JAMA study tracking 222 novel therapeutics approved by the FDA between 2001 and 2010 found only 3 drugs (1.35%) were withdrawn during a median follow-up of 11.7 years. A broader measure in the same study, combining withdrawals with lesser safety actions such as new boxed warnings or FDA safety communications, still found only 71 of 222 drugs (32.0%) had any postmarket safety event, and outright withdrawal accounted for a small fraction of that (3 of 123 total safety events). The claim substantially overstates the frequency of FDA drug withdrawals; the "one in four" figure is not supported by the available postmarket safety literature.