Mary Talley Bowden on spike protein: what the evidence says · JRE #2335
SUBJECT: SPIKE PROTEIN
Not a true/false call. Every claim is logged with its sources; read the exhibits below.
And haven't they shown that the spike protein continues to be produced in the body up to 700 days later? Yes. I mean, that is one study.
What the evidence says 01 / RECORD
The 700-day figure traces to a Yale-led study of post-vaccination syndrome (PVS), released in February 2025 as a medRxiv preprint, which detected the S1 subunit of spike protein circulating in the blood of some PVS participants more than 700 days after their last dose (42 participants and 22 controls). That is a measurement of spike protein detected in a symptomatic subset, not evidence that the body continues to produce spike for 700 days: co-senior author Akiko Iwasaki explicitly said the vaccine mRNA is unlikely to be the source at such a late point, that researchers do not know what is driving the late-phase spike, and that spike was not causally linked to symptoms because other PVS participants had no measurable spike. The authors stressed the work was early-stage, unreplicated, and not yet peer reviewed. Bowden's framing that spike continues to be produced up to 700 days later overstates and mischaracterizes a preliminary detection finding in a small, symptomatic cohort, so the claim is misleading.