Mary Talley Bowden on ivermectin: what the evidence says · JRE #2335
SUBJECT: IVERMECTIN
Not a true/false call. Every claim is logged with its sources; read the exhibits below.
So once I knew it was safe, then I started using it and then I found it worked. And then all in all, I treated well over 6,000 patients and everybody that got early treatment stayed out of the hospital.
What the evidence says 01 / RECORD
Bowden offers an uncontrolled personal case series with no comparison group, so a reported 100 percent out-of-hospital rate among self-selected early-treatment patients cannot establish that any treatment worked. The largest randomized, placebo-controlled trials of the ivermectin-based approach she is known for found no benefit: the TOGETHER trial (New England Journal of Medicine, 2022) concluded that early ivermectin did not result in a lower incidence of hospital admission due to progression of COVID-19. The NIH-funded ACTIV-6 trial, including a higher-dose arm (600 micrograms per kilogram for 6 days), likewise found ivermectin did not improve time to recovery and did not reduce hospitalizations or deaths, stating the findings do not support its use in outpatients with COVID-19. Anecdotal outcome counts from a single practice, absent a control group, are not evidence that the treatment prevented hospitalizations. The claim is unsupported by controlled evidence.