Joe Rogan on health: what the evidence says · JRE #2254
“You look it up on your phone, you instantly know, oh, Ivermectin, the guy who created it, won the Nobel Prize.”
What the evidence says
The 2015 Nobel Prize in Physiology or Medicine was awarded to William C. Campbell and Satoshi Omura for discovering avermectin (the basis for ivermectin), specifically recognizing its effect on parasitic worm diseases such as river blindness and lymphatic filariasis; the prize citation does not reference viral infections or COVID-19, which did not exist until five years later. Ivermectin's established, evidence-based use is as an antiparasitic agent, and its effectiveness against SARS-CoV-2 is a separate question tested directly in randomized controlled trials after 2020. A Cochrane systematic review of six randomized trials (2,860 participants) found ivermectin probably makes little or no difference to mortality in COVID-19 outpatients compared with placebo or usual care, with uncertain or no meaningful benefit on hospitalization, ventilation need, or symptom resolution; a separate peer-reviewed meta-analysis reached similar conclusions. Citing the Nobel Prize as evidence that ivermectin works against COVID-19 conflates the drug's proven antiparasitic mechanism with an unrelated and unproven antiviral use. The claim is misleading: the historical fact (a Nobel Prize for antiparasitic research) is accurate, but it is not evidence of the drug's effectiveness against COVID-19.